By John Francis Laycock
Vasopressin is a hormone which has an more and more vital profile. not just does it play a physiologically major function in renal water legislation however it additionally has different renal activities and performs a task in total cardiovascular keep watch over. much more attention-grabbing is the hot growing to be curiosity in its strength results at the mind, particularly its impression on particular behaviours.
This monograph concerning the polypeptide vasopressin covers all facets with regards to the construction, keep an eye on of liberate, and activities of this molecule in the physique, together with its roles as a hormone and as a imperative neurotransmitter. A attention of the evolution of the molecule around the species and a quick historic standpoint also are incorporated. scientific stipulations linked to hypo- and hyper-production states are thought of including facets of therapy, as well as different medical correlates.
- Introduction to Vasopressin
- Comparative and Evolutionary features of Vasopressin
- The Neurohypophysial procedure: Synthesis and Metabolism of Vasopressin
- Vasopressin Receptors, the Signalling Cascade and Mechanisms of motion
- Pharmacology of the Vasopressin Receptors
- Vasopressin and Its Renal results
- Vasopressin and the Cardiovascular approach
- Vasopressin and Its Interactions with different Hormones and keep an eye on structures
- Understanding the position of Vasopressin within the Hypothalamo-Pituitary Adrenocortical Axis
- Vasopressin: The significant platforms
- Vasopressin Secretion: Mechanisms of keep an eye on of Secretion from the Posterior Pituitary Gland
- Clinical elements of Vasopressin
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Extra info for Perspectives on Vasopressin
Molecular cloning and expression of a V1a arginine vasopressin receptor. J. (2003). Extraordinary diversity in vasopressin (V1a) receptor distributions among wild prairie voles (Microtus ochrogaster): patterns of variation and covariation. , Agre P. (1992). Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. , Kuroshima A. (1964). Effect of lysine vasopressin dimers on blood pressure and some endocrine functions. A (2004). From finch to fish to man: role of aquaporins in body fluid and brain water regulation.
From structure to disease: the evolving tale of aquaporin biology. D. (2007). Comparative water metabolism of Barrow Island macropodid marsupials: hormonal versus behavioural-dependant mechanisms of body water conservation. P. (2008). Individual differences in the allocation of funds in the dictator game associated with length of the arginine vasopressin 1a receptor RS3 promoter region and correlation between RS3 length and hippocampal mRNA. J. (1992). Molecular cloning and expression of a V1a arginine vasopressin receptor.
The sequence in the IGR responsible for both vasopressin and oxytocin gene expression is located in a 178 bp domain immediately downstream of exon 3 of the vasopressin gene. A variety of Fos/Jun 42 J. , 2006). , 2003). Figure 2. Relationship between the vasopressin and oxytocin genes. The two genes lie in tandem arrangement and in reverse order on the same chromosome. The solid arrows refer to the direction of trancription under the influence of each promoter. The dotted arrows refer to the hypothalamic specific enhancing influences.