By E.S. Tai, P.J. Gillies, I. Elmadfa
Nutrigenomics seeks to appreciate the range of the individual’s reaction to foodstuff and the underlying mechanisms wherein meals exert their health-promoting actions. With a deeper molecular knowing of foodstuff, we may perhaps a few day have the capacity to layout diets that actually maximize an individual’s power for wellbeing and fitness and wellbeing. Many Asian societies are presently experiencing a transition in diet-related morbidity and mortality. The id and provision of an optimum nutrition suitable to all of the humans dwelling in Asia is a unprecedented problem as there exists an important variety in nutrition, nutritional consumption styles, neighborhood tradition, and dietary wishes. This quantity explores the position of ethnic range, nutritional styles and genetic version in identifying person nutrient standards through the life-cycle. Conceptualized as an introductory e-book supplying a basic evaluation in addition to particular examples of the purposes of thoughts and strategies, this ebook can assist scientists, clinical, food and different future health pros to profit extra concerning the box of nutrigenomics.
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Additional info for Nutrigenomics Opportunities in Asia: 1st ILSI International Conference on Nutrigenomics, Singapore, December 2005 (Forum of Nutrition)
Wu A, Tseng C-C, Van Den Berg D, Yu MC: Tea intake, COMT genotype and breast cancer in Asian-American women. Cancer Res 2003;63:7526–7529. Dr. A. El-Sohemy Department of Nutritional Sciences, Faculty of Medicine University of Toronto, 150 College St. Toronto, Ont. M5S 3E2 (Canada) Tel. ca El-Sohemy 30 Tai ES, Gillies PJ (eds): Nutrigenomics – Opportunities in Asia. Forum Nutr. Basel, Karger, 2007, vol 60, pp 31–41 Epigenomics and Nutrition Lynne Cobiac Preventative Health National Research Flagship, CSIRO, Adelaide, Australia Abstract Epigenomics or epigenetics refers to the modification of DNA that can influence the phenotype through changing gene expression without altering the nucleotide sequence of the DNA.
Dr. John A. Milner Nutritional Science Research Group, Division of Cancer Prevention National Cancer Institute, 6130 Executive Boulevard, Suite 3164 Rockville, MD 20892 (USA) Tel. gov Milner 24 Tai ES, Gillies PJ (eds): Nutrigenomics – Opportunities in Asia. Forum Nutr. , Canada Abstract Nutrients interact with the human genome to modulate molecular pathways that may become disrupted, resulting in an increased risk of developing various chronic diseases. Genetic polymorphisms affect the metabolism of dietary factors, which in turn affects the expression of genes involved in a number of important metabolic processes.
Do we need to revisit some of the nutrient reference values where in some instances it appears that there are much higher levels of for example folate needed to maintain genome stability ? Nutrients may have a protective effect on one pathway and a nonprotective effect on another and these complex interplays need to be understood. Furthermore, nutrients or bioactives may be protective at one level and nonprotective at a higher level and this effect may depend on the genetic background of the individual.