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For example, habituation may occur and the responses could be different from the beginning to the end of the recording session. Furthermore, cognitive potentials exhibit rich latency and amplitude variability that traditional research based on averaging is not able to exploit for studying complex cognitive processes. Latency variability could be used, for instance, for studying perceptual changes, quantifying stimulus classification speed or task difficulty. In this chapter, state-space modeling for single-trial estimation of EPs was presented in its general form based on Bayesian estimation theory.

American Institute of Chemical Engineers Journal, Vol. 46, pp. ; Thum, C. & Clemens, A. (1974). The artificial beta cell—a continuous control of blood sugar by external regulation of insulin infusion (glucose controlled insulin infusion system). Hormone and Metabolic Research, Vol. 6, pp. ; Von der Mühlen, A. & Brabant, G. (1998). Predictive neural networks for learning the time course of blood glucose levels from the complex interaction of counter regulatory hormones. Neural Computation, Vol. 10, pp.

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