Download Integrating the Neurobiology of Schizophrenia, Volume 78 by Anissa Abi-Dargham, Olivier Guillin PDF

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By Anissa Abi-Dargham, Olivier Guillin

This ebook examines the function that dopamine performs in schizophrenia, studying its function in not just the indicators of the affliction but in addition in its remedy. It additionally stories all neurotransmitters which were implicated in schizophrenia, exploring the genetic info, scientific information implicating the transmitter, and the preclinical info exploring how a transmitter may well engage with dopamine and give a contribution to the dopaminergic phenotype saw within the disorder. This publication will function a tutorial device for teachers, a consultant for clinicians, and be of curiosity to researchers. it's a stable reference for researchers really good in a single specific region and attracted to studying approximately different parts of pathology in schizophrenia and the way they could all feed into one another. The ebook concludes with an total integrative version assembling as a lot of those components as possible.

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Gen. Psychiatry 49, 538–544. , Caron, M. , and Le Moine, C. (2000). DiVerential regulation of the dopamine D1, D2 and D3 receptor gene expression and changes in the phenotype of the striatal neurons in mice lacking the dopamine transporter. Eur. J. Neurosci. 12, 19–26. Ferry, A. , and Price, J. L. (2000). Prefrontal cortical projections to the striatum in macaque monkeys: Evidence for an organization related to prefrontal networks. J. Comp. Neurol. 425, 447–470. , Calvert, C. , Jokel, E. , Fienberg, A.

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Poirier, M. , Alliaire, J. , and Syrota, A. (1991). The estimated density of D2 striatal receptors in schizophrenia. A study with positron emission tomography and 76Br-bromolisuride. Br. J. Psychiatry 158, 346–350. Martinot, J. , Paille`re-Martinot, M. , Dao-Castellana, M. , Allilaire, J. , and Syrota, A. (1994). Central D2 receptors and negative symptoms of schizophrenia. Br. J. Pharmacol. 164, 27–34. Marzella, P. , and Copolov, D. (1997). The binding of both [3H] nemonapride and [3H]raclopride is increased in schizophrenia.

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