By Yerdos Ongarbayev, Zulkhair Mansurov (auth.), Bernard Faye, Yuriy Sinyavskiy (eds.)
The overseas complex study workshop funded by means of NATO and entitled “impact of pollutions on animal and animal items” was once geared up at Almaty (Kazakhstan) on 27–30 September 2007. Thirty-one scientists from 12 nations (Kazakhstan, Kirgizstan, Azerbaijan, Ukraine, Russia, France, nice Britain, Italy, Belgium, Romania and Morocco) awarded meetings at this assembly to proportion their adventure and effects. The programme incorporated 3 major facets: (i) generality at the pollutants state of affairs in valuable Asia and previous Soviet Union republics, (ii) the pollutants quarter and toxins foundation in imperative Asia and Western international locations in relation with animal future health, and (iii) the relationships among soil infection, plant illness and animal items prestige. the current workshop contributed hugely to the trade among scientists giving the chance for researchers from principal Asia to entry to new medical methods and methodologies, and for ecu scientists to evaluate the level of the environmental difficulties during this a part of the area. without doubt that those exchanges have been the most good fortune of the workshop marked by means of very stimulating discussions. Such assembly used to be additionally the chance to place at the first stone of a systematic community excited about the topic of the workshop. the significance of toxins in crucial Asia usually and in Kazakhstan in p- ticular is a well known function and several other references can be found at the resource and localization of pollutants difficulties in these nations. The references also are plentiful at the impression of the environmental mess ups on human health.
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Peoples living in potentially contaminated area such a near municipal solid waste incinerators or in area where extensive chlorinated pesticides have been used are also at higher risk of exposure. 4. INFANT EXPOSURE The major route of exposure for infants in early years of life is consumption of contaminated breast milk, one of the most important sources of dioxins ever. Due to its relatively high lipid content and its human origin, the milk can contain fairly high levels of dioxins. Results obtained from second round of WHO coordinated assessment of dioxin concentration in breast milk of EU Member States in 1993 are presented in Table 8.
Number of possible PCDD, PCDF and PCB congeners Number of isomers Number of chlorine atoms PCDDs 2 10 14 22 14 10 2 1 – – 1 2 3 4 5 6 7 8 9 10 Number of congeners 75 PCDFs 4 16 28 38 28 16 4 1 – – PCBs 3 12 24 42 46 42 24 12 3 1 135 209 Fortunately, most of them do not bio-accumulate in living organisms. Furthermore, for PCDDs and PCDFs, a 2,3,7,8-chlorosubstitution pattern is required for efficient binding to a specific cellular receptor responsible of toxic effects. This represents a group of 7 PCDDs, 10 PCDFs, to which 12 so-called ‘dioxin-like’ (DL) non-ortho and mono-ortho PCB congeners are added because of their structural similarity.
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